Abstract: According to the security requirements of special chemical production processes for dangerous chemicals, the research and application of five chemical process safety techniques were carried out, including the specification of hazardous chemical Material Safety Data Sheet (MSDS) and development of its management information system software, the calculation of DOW Chemical Exposure Index (CEI), Fire & Explosion Index (F&EI) and development of their evaluation software, chemical process dynamic early warning technology study and software development based on the artificial immune diagnosis algorithm, safety accident investigation management technology research and software development using predefined tree and fault tree analysis strategy. A chemical process safety risk management technology system was built in the paper, and we tried to control the safety risk of the special dangerous chemical production processes in the full production life cycle.

摘要： 根据危险化学品生产所用特种化工过程的安全管控需求，对5项化工安全管控工程技术进行了研究与应用，包括危险化学品安全技术数据说明书（Material Safety Data Sheet， MSDS）及其管理软件开发、DOW化学暴露指数（Chemical Exposure Index，CEI）的计算及其评估软件开发、DOW火灾爆炸指数（Fire & Explosion Index，F&EI）的计算及其评估软件开发、基于人工免疫诊断算法的化工过程动态预警技术及其软件开发、基于预定义树和故障树的安全事故调查分析管理技术及其软件开发等，力求构建化工过程安全风险管控技术体系，从事前、事中和事后等多方面对特种化工过程进行全方位安全管控。

关键词: 化工安全工程 MSDS DOW 化学指数 动态预警 安全事故调查, chemical process safety MSDS DOW chemical index dynamic warning safety accident investigation